Saturday, 6 April 2013

Hillary Clinton headlines NY women's conference

Former Secretary of State Hillary Rodham Clinton addresses the Vital Voices Global Partnership 2013 Global Leadership Awards gala at the Kennedy Center for the Performing Arts in Washington, Tuesday, April 2, 2013. (AP Photo/Cliff Owen)

Former Secretary of State Hillary Rodham Clinton addresses the Vital Voices Global Partnership 2013 Global Leadership Awards gala at the Kennedy Center for the Performing Arts in Washington, Tuesday, April 2, 2013. (AP Photo/Cliff Owen)

NEW YORK (AP) ? Former Secretary of State Hillary Rodham Clinton said Friday at a forum on global women's issues that the rights of women represent "the unfinished business of the 21st century" in the United States and around the world, receiving a rapturous reception for one of her first speeches since departing the Obama administration.

Clinton, a potential 2016 presidential candidate, offered no new clues about her future at the annual two-day Women in the World summit. She said the mission of gender equality is not limited to the developing world, pointing to the need for more women in the United States to achieve equality with men.

"If America is going to lead the way we expect ourselves to lead, we need to empower women here at home to participate fully in our economy and our society. We need to make equal pay a reality," Clinton said, pointing to the need to extend family and medical leave and encourage women and girls to pursue careers in math and science. "We need to invest in our people so they can live up to their own God-given potential."

"This truly is the unfinished business of the 21st century, and it is the work we are called to do," Clinton said. "I look forward to being your partner in all the days and years ahead. Let's keep fighting for opportunity and dignity."

The former first lady and New York senator was the keynote speaker at a star-studded conference focusing on women across the globe, featuring appearances by actresses Angelina Jolie and Meryl Streep. It was Clinton's second high-profile speech this week and coincided with the announcement Thursday of her new memoir about her years as secretary of state.

Clinton has addressed the forum before, but the speculation about her future was an undercurrent in the audience. Tina Brown, editor in chief of Newsweek and the Daily Beast, the summit's sponsor, received loud cheers during her introduction of Clinton when she teased, "Of course, the big question now about Hillary is what's next."

Clinton said the world was "changing beneath our feet," urging advocates to encourage developing nations around the globe to embrace a 21st-century approach that makes the rights of women a central issue in foreign and domestic policy.

Friday's agenda included a panel on technology moderated by Clinton's daughter, Chelsea, discussions on women's rights in India and Libya and a luncheon interview with Susan Rice, U.S. ambassador to the United Nations.

Underscoring the plight of women across the globe, attendees saw an emotional moment on Thursday from Jolie, who introduced Malala Yousafzai, the Pakistani teenager who was shot in the head by the Taliban for advocating for girls' education.

"Today I'm going to announce the happiest moment of my life," the 15-year-old said in a brief video from Britain, wearing a bright red headscarf and at one point shyly covering her face with her hands. She said that thanks to the new "Malala's Fund," which she will administer, a new school in her homeland would be built for 40 girls. "Let us turn the education of 40 girls into 40 million girls," she said.

Malala has garnered huge global attention since she was shot in the head in October by Taliban attackers angered by her activism. She was brought to Britain for treatment and surgery, including skull reconstruction. She's now started attending school there. She recently signed a deal to write her memoir, and she was also shortlisted for Time Magazine's "Person of the Year" in 2012.

Jolie gave a poignant rendition of her story. "Here's what they accomplished," she said of Malala's attackers. "They shot her point blank range in the head ? and made her stronger. The brutal attempt to silence her voice made it stronger."

After Jolie's introduction, Brown, who created the Women in the World summit, now in its fourth year, told the audience that Jolie had just committed $200,000 personally to the fund, which was established by Vital Voices, with a donation from the Women in the World Foundation.

Streep was there to honor another activist, Inez McCormack of Northern Ireland, who died in January of cancer. At the first summit in 2010, Streep had played McCormack in a short play, called "Seven," with McCormack herself watching from the audience. Streep spoke some lines from the play on Thursday evening in a flawless Irish accent.

___

Online: http://womenintheworld.org/pages/women-in-the-world-summit-2013

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-05-Women's%20Conference/id-4e6911005121431bb0baeb8c7a8ebac2

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Friday, 5 April 2013

Wild mice have natural protection against Lyme borreliosis

Wild mice have natural protection against Lyme borreliosis [ Back to EurekAlert! ] Public release date: 4-Apr-2013
[ | E-mail | Share Share ]

Contact: Barbara Tschirren
barbara.tschirren@ieu.uzh.ch
41-446-354-777
University of Zurich

Springtime spells tick-time. Lyme borreliosis is the most common tick-borne disease in Switzerland: around 10,000 people a year become infected with the pathogen. The actual hosts for Borrelia, however, are wild mice. Like in humans, the pathogen is also transmitted by ticks in mice. Interestingly, not all mice are equally susceptible to the bacterium and individual animals are immune to the pathogen. Scientists from the universities of Zurich and Lund headed by evolutionary biologist Barbara Tschirren reveal that the difference in vulnerability among the animals is genetic in origin.

Protective gene variant

Tschirren and colleagues examined wild mice for signs of a Borrelia infection in a large-scale field study. Borrelia afzelii the scientific name for the bacteria feed on mouse blood. The researchers discovered that mice with a particular variant of the antigen receptor TLR2 were around three times less susceptible to Borrelia. "The immune system of mice with this receptor variant recognizes the pathogen better and can trigger an immune response more quickly to destroy the Borrelia in time," says Tschirren. Infected mice exhibit similar symptoms to humans especially joint complaints. Consequently, in the wild infected mice probably do not survive for very long and weakened animals soon fall victim to foxes and birds of prey.

Arms race between mice and Borrelia

The protective gene variant is advantageous for its carriers and, according to the researchers, gradually becoming prevalent in the mouse population. Nonetheless, it is unlikely that all mice will one day be resistant to Borrelia. "The increasing resistance in the host is bound to lead to adaptations in Borrelia," predicts Tschirren. "We can observe the evolutionary adaptation through the rearmament in mice and the pathogen."

People also have the antigen receptor TLR2, but not the resistant gene variant observed in mice. Whether the evolutionary arms race between mice and Borrelia will have repercussions for people remains to be seen. According to Tschirren, the bacterium does not necessarily have to become more aggressive for humans.

###

Literatur:

Barbara Tschirren, Martin Andersson, Kristin Scherman, Helena Westerdahl, Peer R. E. Mittl, and Lars Rberg. Polymorphisms at the innate immune receptor TLR2 are associated with Borrelia infection in a wild rodent population. Proceedings of the Royal Society B, 20130364. April 3, 2013. doi: 10.1098/rspb.2013.0364

Contact:

Prof. Barbara Tschirren
Institute of Evolutionary Biology and Environmental Studies
University of Zurich
Phone. +41 44 635 47 77
E-mail: barbara.tschirren@ieu.uzh.ch


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Wild mice have natural protection against Lyme borreliosis [ Back to EurekAlert! ] Public release date: 4-Apr-2013
[ | E-mail | Share Share ]

Contact: Barbara Tschirren
barbara.tschirren@ieu.uzh.ch
41-446-354-777
University of Zurich

Springtime spells tick-time. Lyme borreliosis is the most common tick-borne disease in Switzerland: around 10,000 people a year become infected with the pathogen. The actual hosts for Borrelia, however, are wild mice. Like in humans, the pathogen is also transmitted by ticks in mice. Interestingly, not all mice are equally susceptible to the bacterium and individual animals are immune to the pathogen. Scientists from the universities of Zurich and Lund headed by evolutionary biologist Barbara Tschirren reveal that the difference in vulnerability among the animals is genetic in origin.

Protective gene variant

Tschirren and colleagues examined wild mice for signs of a Borrelia infection in a large-scale field study. Borrelia afzelii the scientific name for the bacteria feed on mouse blood. The researchers discovered that mice with a particular variant of the antigen receptor TLR2 were around three times less susceptible to Borrelia. "The immune system of mice with this receptor variant recognizes the pathogen better and can trigger an immune response more quickly to destroy the Borrelia in time," says Tschirren. Infected mice exhibit similar symptoms to humans especially joint complaints. Consequently, in the wild infected mice probably do not survive for very long and weakened animals soon fall victim to foxes and birds of prey.

Arms race between mice and Borrelia

The protective gene variant is advantageous for its carriers and, according to the researchers, gradually becoming prevalent in the mouse population. Nonetheless, it is unlikely that all mice will one day be resistant to Borrelia. "The increasing resistance in the host is bound to lead to adaptations in Borrelia," predicts Tschirren. "We can observe the evolutionary adaptation through the rearmament in mice and the pathogen."

People also have the antigen receptor TLR2, but not the resistant gene variant observed in mice. Whether the evolutionary arms race between mice and Borrelia will have repercussions for people remains to be seen. According to Tschirren, the bacterium does not necessarily have to become more aggressive for humans.

###

Literatur:

Barbara Tschirren, Martin Andersson, Kristin Scherman, Helena Westerdahl, Peer R. E. Mittl, and Lars Rberg. Polymorphisms at the innate immune receptor TLR2 are associated with Borrelia infection in a wild rodent population. Proceedings of the Royal Society B, 20130364. April 3, 2013. doi: 10.1098/rspb.2013.0364

Contact:

Prof. Barbara Tschirren
Institute of Evolutionary Biology and Environmental Studies
University of Zurich
Phone. +41 44 635 47 77
E-mail: barbara.tschirren@ieu.uzh.ch


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/uoz-wmh040413.php

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Thursday, 4 April 2013

The Most Common Issues Faced By Human Resource Managers ...

There are many significant human resources issues facing both employers and employees today. With the development of both small and larger-scale businesses, the need for human resource management ? and the foresight and ability to avoid the problems that accompany it ? is growing. What are the main issues faced by employers and employees, and how can these be nullified?

Recruitment and Outsourcing

The best way to effectively manage a workforce is arguably to know how best to recruit that workforce ? after all, it?s far easier to work with a group of people that you are already familiar with through the recruitment process. Perfecting the different facets of this process, from attending careers events and writing effective and accurate job advertisements right through to knowing the best way to conduct an interview, are key methods to minimising the problems any HR executive may face in the future.

Recruitment has become a marketing exercise in recent years. Knowing how to properly generate interest in a company or a specific job placement is paramount to recruiting the right candidates. Worthwhile employees are increasingly seeking jobs that address their need for a better work-home-family balance, and good HR departments are becoming more aware of this. Companies also need to consider the prospect of job security for employees, as they are often more concerned with stability, health benefits and their employment in unstable economic conditions than ever before.

Outsourcing is also a major part of human resource management?s role in a company, as many companies ? particularly in an economic downturn ? choose to hire freelance workers to complete additional tasks rather than taking on salaried employees in-house. When outsourcing, human resource managers do not need to consider overheads like taxes, working equipment costs or benefits, as these are met by the freelancers themselves.

Rights, Discrimination and Conflict Resolution

Many countries are now governed by strict laws that make rights abuses and discrimination in the workplace severely punishable. As it is illegal in these countries to discriminate based on age, gender, religion and race, HR managers need to be aware of this and their methods need to reflect this. Most companies see diversity as forward-thinking and teamwork-promoting, as well as fostering a sense of equality. As well as following recruitment protocols that take diversity ? and its legal implications - into account, human resource management departments may need to prepare for higher levels of disagreements and more distinct methods of resolution.

Conflict resolution is a major part of a HR manager?s job in that it is always easier and cheaper to keep an existing employee than to recruit and train a new one. As such, the conflicts that arise from different departments, workers and employment levels need to be resolved effectively. These can range from property theft and destruction and physical and verbal harassment to management incompetence and payroll management issues.

Training and Safety

For almost every business, training is a major part of day-to-day operations, as every business is different and therefore has different practices to follow. Training is also an investment process ? new, potentially brilliant candidates all need to start somewhere, and investing in talent through both basic training and preparing senior executives for the next step up can pay off when done right by organised and skilled HR managers. It is HR?s responsibility to fit the training around day-to-day work, factoring in time, financial costs and third-party coordination for each company department and budget.

Safety is also a major part of training organisation, as many businesses follow practices that minimise risk and promote safety, whether they are using specialist, potentially dangerous equipment or not. Even incorrectly-positioned chairs or too bright LED computer monitors can cause extensive health issues, so everything right down to these small issues need to be considered when organising staff and departments.

These are only some of the major issues faced by human resource departments today ? there are many more, much smaller problems that can slip under the radar. Rather than investing in more employees or working longer hours to keep up with every single eventuality, it might be more worthwhile for the company?s bank balance and the HR manager?s work-life balance to invest in some new HR software instead ? so the management can keep their eye on the bigger issues.

This is a guest post.

Source: http://www.managers.org.uk/practical-support/management-community/blogs/most-common-issues-faced-human-resource-managers

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Palestinian protester killed by Israeli army fire

JERUSALEM (AP) ? Israeli forces shot and killed a teenage Palestinian protester during a clash in the West Bank late Wednesday, raising tensions already heightened by the death of a Palestinian prisoner and renewed fighting between Israel and Gaza militants.

The late night killing capped a day of rioting throughout the West Bank in protest at the prisoner's death from cancer and raised the likelihood of further unrest in the Palestinian territories Thursday.

Mohammed Ayyad, a spokesman for the Palestinian Red Crescent, said a 17-year-old Palestinian was killed in a clash between the Israeli army and Palestinian stone-throwers at a checkpoint near the West Bank city of Tulkarem. He was hit by a bullet in the chest, Ayyad said. The spokesman did not provide the youth's name.

The Israeli military said several Palestinians hurled firebombs at a military post near Tulkarem, and soldiers at the post fired a live round at the protesters, hitting one. The army said it was reviewing the circumstances of the incident.

Early Wednesday, Palestinian militants launched several rockets into southern Israel and Israeli aircraft struck targets in the Gaza Strip in the heaviest exchange of fire between the sides since a cease-fire ended a major flare-up last year.

There were no casualties, but the violence nonetheless threatened to shatter the calm that has prevailed for more than four months. Israel's new defense minister issued a stern warning.

"We will not allow shooting of any sort (even sporadic) toward our citizens and our forces," Moshe Yaalon, a former military chief of staff, said in a statement.

By nightfall Wednesday, calm appeared to have returned on that front. A small al-Qaida-influenced group was suspected. The rocket fire coincided with unrest in the West Bank over the death of a Palestinian prisoner.

Yaalon said he holds the Islamic militant Hamas, which has ruled Gaza since 2007, responsible for all such attacks from the seaside strip.

Israel launched an offensive against Hamas last November in response to an increase in rocket fire from Gaza. During eight days of fighting, Israel carried out hundreds of airstrikes in Gaza, while Gaza militants fired hundreds of rockets into Israel. More than 160 Palestinians, including dozens of civilians, and six Israelis were killed in the fighting before Egypt brokered a truce.

In recent weeks, there have been several rocket attacks, including one as President Barack Obama was visiting Israel two weeks ago. Overnight Wednesday, Israel responded for the first time by striking a pair of empty fields in northern and eastern Gaza.

Around the time Yaalon was speaking on Wednesday morning, two more rockets exploded in the Israeli border town of Sderot, according to police. Air raid sirens sounded, and people on their way to work and school took cover. No injuries were reported.

The Israeli military said a total of five rockets were fired within 24 hours, including two that exploded prematurely inside Gaza.

Under the cease-fire, Israel pledged to halt its policy of attacking militant leaders and to ease a blockade it imposed on Gaza after the Hamas takeover in 2007. Hamas pledged to halt rocket attacks on Israel. A number of smaller militant groups also operate in Gaza, including groups that draw inspiration from the al-Qaida global terror network.

U.N. Mideast envoy Robert Serry appealed for calm in a statement. "It is of paramount importance to refrain from violence in this tense atmosphere and for parties to work constructively in addressing the underlying issues," he said.

Ihab Ghussein, the Hamas government spokesman, accused Israel of using the airstrikes to "divert the attention" from unrest in Israeli prisons.

Palestinian prisoners have been rioting and hunger striking since a 64-year-old prisoner died of throat cancer on Tuesday. Palestinians blamed Israel for the man's death, saying he was not given proper medical care. The prisoner, Maysara Abu Hamdiyeh, was serving a life sentence for his role in a foiled attempt to bomb a busy cafe in Jerusalem in 2002.

Einav Shimron Grinbaum, spokeswoman of Israel's health ministry, said an autopsy performed Wednesday found a cancerous growth in Abu Hamdiyeh's throat and secondary cancerous growths in his neck, chest, lungs, liver, and spinal cord. She said hospital records showed he was a heavy smoker. The head of the Palestinian pathological institute also participated in the autopsy, she said.

At protests across the West Bank Wednesday afternoon, hundreds of Palestinians threw rocks and rolled burning tires at soldiers, prompting a response with tear gas, the Israeli military said.

In Ramallah, protesters waved pictures of Abu Hamdiyeh and chanted "with our souls and blood we will redeem the prisoner."

Israel's chief military spokesman, Brig. Gen. Yoav Mordechai, accused the Palestinian Authority, which governs in the West Bank, of exploiting the death to "resume popular protests."

Prisons Authority spokeswoman Sivan Weizman said Abu Hamdiyeh was treated by Israeli specialists and died in a hospital in Beersheba.

Weizman said almost all of the 4,600 Palestinian prisoners detained by Israel refused their breakfasts Wednesday morning in a symbolic act of protest.

In a separate development, Israel's defense minister issued a tough warning to battling forces in Syria, saying Israel would respond to any cross-border provocations.

On Tuesday, the Israeli military said a mortar shell exploded on its side of the frontier in the Golan Heights. The military said its soldiers returned the fire and said they scored a direct hit.

"Israel has no intention of ignoring fire from Syria toward Israeli territory, incidental or not, and will respond with a firm hand," Yaalon said. "As far as we are concerned, the Syrian regime is to be held responsible for everything happening in its territory."

Israel, which has warily watched the fighting in Syria raging close to its frontier, is concerned that al-Qaida-linked groups fighting alongside the rebels could set their sights on Israel after the civil war ends.

Source: http://news.yahoo.com/palestinian-protester-killed-israeli-army-fire-214108806.html

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Wednesday, 3 April 2013

Feeling hungry may protect the brain against Alzheimer's disease

Apr. 2, 2013 ? The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger pangs, and related hormonal pathways, may be as important to the much-discussed value of "caloric restriction" as actually eating less.

Caloric restriction is a regimen where an individual consumes fewer calories than average, but not so few that they become malnourished. Studies in many species have suggested that it could protect against neurodegenerative disorders and extend lifespans, but the effect has not been confirmed in human randomized clinical trials.

Efforts to understand how cutting calories may protect the brain have grown increasingly important with news that American Alzheimer's deaths are increasing, and because the best available treatments only delay onset in a subset of patients.

Study authors argue that hormonal signals are the middlemen between an empty gut and the perception of hunger in the brain, and that manipulating them may effectively counter age-related cognitive decline in the same way as caloric restriction.

"This is the first paper, as far as we are aware, to show that the sensation of hunger can reduce Alzheimer's disease pathology in a mouse model of the disease," said Inga Kadish, Ph.D., assistant professor in the Department of Cell, Developmental and Integrative Biology (CDIB) within the School of Medicine at the University of Alabama at Birmingham. "If the mechanisms are confirmed, hormonal hunger signaling may represent a new way to combat Alzheimer's disease, either by itself or combined with caloric restriction."

The team theorizes that feeling hungry creates mild stress. That, in turn, fires up metabolic signaling pathways that counter plaque deposits known to destroy nerve cells in Alzheimer's patients. The idea is an example of hormesis theory, where damaging stressors like starvation are thought to be good for you when experienced to a lesser degree.

To study the sensation of hunger, the research team analyzed the effects of the hormone ghrelin, which is known to make us feel hungry. They used a synthetic form of ghrelin in pill form, which let them control dosage such that the ghrelin-treated mice felt steadily, mildly hungry.

If it could be developed, a treatment that affected biochemical pathways downstream of hunger signals might help delay cognitive decline without consigning people to a life of feeling hungry. Straight caloric restriction would not be tolerable for many persons over the long-run, but manipulating post-hunger signaling might.

This line of thinking becomes important because any protective benefit brought about by drugs or diets that mildly adjust post-hunger signals might be most useful if started in those at risk as early in life as possible. Attempts to treat the disease years later -- when nerve networks are damaged enough for neurological symptoms to appear -- may be too late. In the current study, it was long-term treatment with a ghrelin agonist that improved cognitive performance in mice tested when they had reached an advanced age.

Study details The study looked at whether or not the feeling of hunger, in the absence of caloric restriction, could counter Alzheimer's pathology in mice genetically engineered to have three genetic mutations known to cause the disease in humans.

Study mice were divided into three groups: one that received the 'synthetic ghrelin' (ghrelin agonist), a second that underwent caloric restriction (20 percent less food) and a third group that was fed normally. Study measures looked at each group's ability to remember, their degree of Alzheimer's pathology and their level of related, potentially harmful immune cell activation.

Results of such studies are most appropriately presented in terms of general trends in the data and statistical assessments of their likelihood if only chance factors were in play, a trait captured in each result's P value (the smaller the better). Thus, the first formal result of the study are that, in mice with the human Alzheimer's mutations, both the group treated with the ghrelin agonist LY444711 and the group that underwent caloric restriction performed significantly better in the a water maze than did than mice fed normally (p=0.023).

The water maze is the standard test used to measure mouse memory. Researchers put mice in a pool with an invisible platform on which they could rest, and measured how quickly the mice found the platform in a series of tests. Mice with normal memory will remember where the platform is, and find it more quickly each time they are placed in the pool. Ghrelin agonist-treated mice found the hidden platform 26 percent faster than control mice, with caloric restricted mice doing so 23 percent faster than control mice.

The second result was a measure of the buildup of a cholesterol-related protein called amyloid beta in the forebrain, an early step in the destruction of nerve cells that accompanies Alzheimer's disease. The formal amyloid beta results show that mice either treated with the ghrelin agonist or calorically restricted had significantly less buildup of amyloid beta in the dentate gyrus, the part of the brain that controls memory function, than mice fed normally (i.e., control, 3.95?0.83; LY, 2.05?0.26 and CR, 1.28?0.17%, respectively; Wilcoxon p=0.04).

The above results translate roughly into a 67 percent reduction of this pathology in caloric-restricted mice as compared to control mice, and a 48 percent reduction of amyloid beta deposits when comparing the ghrelin-treated mice with the control group. These percentages are neither final nor translatable to humans, but are simply meant to convey the idea of "better."

Finally, the team examined the difference in immune responses related to Alzheimer's pathology in each of the three groups. Microglia are the immune cells of the brain, engulfing and removing invading pathogens and dead tissue. They have also been implicated in several diseases when their misplaced activation damages tissues. The team found that mice receiving the ghrelin agonist treatment had both reduced levels of microglial activation compared to the control group, similar to the effect of caloric restriction.

The ghrelin agonist used in the study does not lend itself to clinical use and will not play a role in the future prevention of Alzheimer's disease, said Kadish. It was meant instead to prove a principle that hormonal hunger signaling itself can counter Alzheimer's pathology in a mammal. The next step is to understand exactly how it achieved this as a prerequisite to future treatment design.

Ghrelin is known to create hunger signals by interacting with the arcuate nucleus in the part of the brain called the hypothalamus, which then sends out signaling neuropeptides that help the body sense and respond to energy needs. Studies already underway in Kadish's lab seek to determine the potential role of these pathways and related genes in countering disease.

"Our group in the School of Public Health was studying whether or not a ghrelin agonist could make mice hungry as we sought to unravel mechanisms contributing to the life-prolonging effects of caloric restriction," said David Allison, Ph.D., associate dean for Science in the UAB School of Public Health and the project's initiator.

"Because of the interdisciplinary nature of UAB, our work with Dr. Allison led to an amazing conversation with Dr. Kadish about how we might combine our research with her longtime expertise in neurology because caloric restriction had been shown in early studies to counter Alzheimer's disease," said Emily Dhurandhar, Ph.D., a trainee in the UAB Nutrition Obesity Research Center and first study author. "The current study is the result."

About the research team Along with Kadish, Allison, and Dhurandhar, Thomas van Groen, Ph.D., associate professor in UAB's CDIB co-authored the paper.

Eli Lilly donated of the ghrelin agonist used in the study. This work was also supported by Alzheimer's of Central Alabama, the National Institutes of Health Obesity Training Grant (T32DK062710), and the National Institutes of Health Behavioral Assessment Core of UAB (P30 NS47466). Allison disclosed consulting relationships with industry, the details of which are included in the PLOS ONE article.

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Story Source:

The above story is reprinted from materials provided by University of Alabama at Birmingham. The original article was written by Greg Williams.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Emily J. Dhurandhar, David B. Allison, Thomas van Groen, Inga Kadish. Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer's Disease Pathology in a Mouse Model. PLoS ONE, 2013; 8 (4): e60437 DOI: 10.1371/journal.pone.0060437

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/DkDJdyQL3gE/130402182457.htm

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State Cites Yorktown for Shabby Cleanup of Sporting Club Site | The ...

Councilman Vishnu Patel on the Mohegan site that is being fined by DEC.

Councilman Vishnu Patel on the Mohegan site that is being fined by DEC.

The Town of Yorktown was issued a violation last month by the state Department of Environmental Conservation for leaving hazardous materials buried on the site of the former Holland Sporting Club in Mohegan Lake.

DEC Region 3 spokesperson Wendy Rosenbach confirmed Thursday a notice of violation was issued to the town ?within the past two weeks? but was unable to provide a specific date or details. Rosenbach said Yorktown was ordered to remove a lot of the remaining debris that wound up in the foundation of some of the 14 dilapidated buildings that the town?s Highway Department tore down last summer.

A crew of highway workers was on the property Thursday and Friday morning but fled the scene immediately after Yorktown Councilman Vishnu Patel, who has been questioning the environmental integrity of the land and has been regularly in contact with the DEC, and a reporter visited the premises.

?What are they hiding? This has to be done right,? Patel remarked. ?This is very sensitive land there. I care about the environment. My mission is to clean it up. All I care about is the taxpayers.?

The Town Board gave Highway Superintendent Eric DiBartolo the go-ahead last year to fill 49 trash bins with 304 tons of debris that was gathered from ripping down the buildings, some of which dated back to the 1920s. Supervisor Michael Grace has repeatedly touted the estimated $60,000 savings to the town utilizing town employees instead of outside contractors but Patel said there is a price to pay when environmental safeguards are ignored.

?Being penny wise and a pound foolish is a big problem,? Patel said. ?They?re going to pay the price on this one because they have to clean it up.?

Former Supervisor Susan Siegel said when the Town Board voted a few years ago while she was still in office to seek outside contractors it was convinced the job was too much for the Highway Department.

?When it was touted that they saved money, they didn?t save money because they didn?t do the same job,? said Siegel, who has announced her intention to challenge Grace in November.

Grace contended Thursday he had not seen any paperwork from the DEC regarding the violation, saying he was only advised by DiBartolo about it. He also maintained the DEC only acted because Patel was ?rattling their cage.?

In addition, he explained the wood chips that were used to fill seven feet deep holes where the buildings foundations were only intended to be a temporary measure and would be replaced with clean dirt the town will receive from the state Department of Transportation.

?I don?t see what the big deal is,? Grace said. ?I was there when the DEC inspected it and they didn?t seem to have any problem with it.?

When asked why highway crews would bolt from the property when visitors arrived, Grace remarked ?I wouldn?t read much into it. They may have had other things to do.?

The future of the Holland Sporting Club site is expected to be discussed during a Town Board work session on April 9. A recent proposal to build ball fields there was soundly denounced by residents, and not recommended by the town?s Parks and Recreation Advisory Council.

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Source: http://www.theexaminernews.com/state-cites-yorktown-for-shabby-cleanup-of-sporting-club-site/?utm_source=rss&utm_medium=rss&utm_campaign=state-cites-yorktown-for-shabby-cleanup-of-sporting-club-site

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USO Supports Military Children When They Need it Most

USO Kicks Off April ?Month of the Military Child? with Events and Activities Around the Globe.

Arlington, VA (PRWEB) April 01, 2013

April is nationally recognized as Month of the Military Child and the USO will honor our nation?s youngest heroes with events and activities at USO locations worldwide. The USO has a 72-year history of supporting military children as they cope with unique challenges like the stresses of being away from a parent during deployment and what it?s like when a parent returns home ?different?- adjusting to life with visible and invisible wounds. In the 10 years since the United States? invasion of Iraq, the USO has continually adapted to meet the needs of our nation?s military families.

There are more than 1.2 million children with a parent in the United States military, of those 220,000 have a parent deployed and many have endured the stresses of multiple deployments. Whether they are worrying about a loved one in harm?s way or facing the challenges that can arise when families are reunited after a lengthy deployment, the USO is standing with them.

?The USO adapts to meet the needs of those who need us most. To support our nation?s youngest heroes, we have made a commitment to providing programs and services to help them lead strong family lives today, tomorrow and in the future,? said Susan Thomas, Senior Vice President, USO Warrior and Family Care. ?The USO provides opportunities for families to stay connected during deployment, comforting them when they are facing unimaginable life challenges, and support their transition when mom or dad returns home.?

This month the USO will support our nation?s littlest heroes with USO programs and events worldwide including:

With You All the Way: Trevor Romain will be engaging in activities around the Nation?s Capitol including tour stops at Fort Meade and Joint Base Andrews in Maryland, as well as Fort Belvoir in Virginia, where he will officially kick off the Month of the Military Child in a presentation alongside the installation command. Romain will also engage with Congressional leaders on Capitol Hill during an assembly event for the ?Taking Care of You? kits (benefitting children of wounded soldiers) and join a panel of three other family and child health professionals at the second annual With You All the Way Symposium at Fort Belvoir. With You All the Way will then travel to Twentynine Palms, CA to deliver presentations to children of those stationed at the Marine Combat Training Center.

The Little CHAMPS: The book ?The Little CHAMPS: Child Heroes Attached to Military Personnel? follows the children of five service members, each representing a branch of the military, as they cope with deployments, saying goodbye, and when a parent returns home wounded. In addition to providing copies of the book to USO Centers Worldwide, this April the USO will bring the book?s author, Debbie Fink, to the Pacific Region to present her book and educational curriculum to nearly 6,000 military children.

Sesame Street/USO Experience: The Sesame Street/USO Experience for Military Families made its debut in July 2008, to help families deal with the challenges of deployment and homecomings. Since its inception, the tour has taken its message to more than 368,000 troops and military families and performed 631 shows on 145 military installations in 33 states and 11 countries. Additionally, the tour logged more than 122,000 miles and distributed more than 2 million giveaways. This spring, the tour will once again be hitting the road to visit 42 installations in 8 countries in the Europe and Pacific regions.

USO Centers: USO centers provide a warm and comforting place where troops can connect with home via Internet or telephone. USO centers also provide a place for military families to come together and connect with one another to support each other in difficult times. USO Center events focused on military children for Month of the Military Child include:

????Project Cinderella: This annual event hosted by USO of Metropolitan Washington is designed to prepare ????military women for formal functions through fun, interactive workshops and demonstrations lead by ????industry experts. Workshops include dressing right for one?s body type, beauty on a budget, fun with ????make-up/hair and etiquette. The event will also include pampering activities, makeovers, photo shoot, ????crowning ?Project Cinderella 2013? and a Princess Tea party. The grand finale consists of a dress and ????accessory boutique giveaway.

????Spring Fling: USO Las Vegas is collaborating with a number of community military support groups to ????sponsor a "Spring Fling" carnival to celebrate the importance of military children in our community.

????USO Story Time: This event, hosted by USO Fort Hood in Texas, is designed for preschoolers to promote ????early literacy. Activities will include breakfast, story time, and craft activities.

????Liggett Carnival: USO Bay Area will be out at Fort Hunter Liggett in California to celebrate military children ????with a carnival and fun fair offering games, prizes, and food.

Last year, the USO connected military families during separation with more than 3 million free phone calls. In addition, troops made more than 43,000 United Through Reading recordings, affording deployed parents the opportunity to read along with their children back home.

In a recent survey conducted among active duty military and their dependents, USO?s support of military families ranked among the highest valued services the USO provides to our nation?s military. Programs like With You All the Way saw an increase of 19% over last year.

Following a tour stop in Germany last fall, Trevor Romain and the With You All the Way program received this note from a military spouse:


?Dear Mr. Romain. Thank you for coming to Patch Elementary School in Stuttgart. My son did not stop talking about your visit all the way home in the car. Then something happened when we got to the house. You see my husband was hurt and he lost part of his leg and my son seems ashamed and angry about what happened. He always wanted to take his anger out by himself and stay locked in his room alone and did not want to deal with his dad. And it was so hard for my husband. He said that kind of pain was worse than his injury. Today when he came home my son wrote a letter to his dad and said he loved him and wanted to help him get better. I?m not sure what you said to him but thank you and Mr. Woody and the USO for your presentation and for helping our kids on the bases. You just don?t know how much it means to us. I cannot thank you enough for your help.?

Visit http://www.uso.org to learn how the USO is always by the side of those who need us most: deployed troops, military families, wounded, ill and injured troops and their caregivers and families of the fallen.

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About the USO

The USO lifts the spirits of America?s troops and their families millions of times each year at hundreds of places worldwide. We provide a touch of home through centers at airports and military bases in the U.S. and abroad, top quality entertainment and innovative programs and services. We also provide critical support to those who need us most, including forward-deployed troops, military families, wounded warriors and families of the fallen. The USO is a private, non-profit organization, not a government agency. Our programs and services are made possible by the American people, support of our corporate partners and the dedication of our volunteers and staff.

In addition to individual donors and corporate sponsors, the USO is supported by President?s Circle Partners: American Airlines, AT&T, Clear Channel, The Coca-Cola Company, jcpenney, Jeep, Kangaroo Express, Kroger, Lowe?s, Northrop Grumman Corporation, Procter & Gamble, and TriWest Healthcare Alliance and Worldwide Strategic Partners: BAE Systems, The Boeing Company, Lockheed Martin, Microsoft Corporation and TKS Telepost Kabel-Service Kaiserslautern GmbH & Co. KG. We are also supported through the United Way and Combined Federal Campaign (CFC-11381). To join us in this patriotic mission, and to learn more about the USO, please visit uso.org.

Andrea Sok
USO
480-570-2329
Email Information

Source: http://news.yahoo.com/uso-supports-military-children-most-160614668.html

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